The Entourage Effect

The many components in cannabis have different properties and act independently from one another. However, studies have shown that their combined effect can be safer and more efficient than when there are isolated – so the medicinal impact of the whole plant is greater than the sum of its parts. Apart from cannabinoids, other compounds – like terpenoids, which give the plants their color, aroma and flavor – are integral parts of this combination. This synergy among phytotherapeutic compounds is called the “entourage effect”.

Phytotherapeutic medicines that take advantage of the entourage effect can have a broader effect on the body, enhancing the absorption of active ingredients, increasing resistance to bacterial infections and minimizing adverse effects. Research has shown that CBD, for example, reduces some of the adverse effects of THC, like its psychotropic effect.

New research will broaden our knowledge of the entourage effect and its therapeutic potential as we discover more about the effects of other phytocannabinoids like cannabinol (CBN), cannabigerol (CBG), cannabivarin (CBV), canabidivarin (CBDV), tetrahydrocanabivarin (THCV), and terpenoids like myrcene, linalool and beta-caryophyllene.

Entourage Phytolab works to produce medicines from plant-derived raw materials that offer the best possible combination of these compounds for every kind of ailment or condition, exploring all of the beneficial potential of the entourage effect.